Advances in Functional and Reparative Neurosurgery (Acta by Jin Woo Chang, Yoichi Katayama, Takamitsu Yamamoto

By Jin Woo Chang, Yoichi Katayama, Takamitsu Yamamoto

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Rigidity, bradykinesia, axial symptoms, facial expression and dyskinesia were all improved, although to a lesser extent, while speech was not improved. 001). According to the time of follow-up, 4 groups were classified (4–12 months, 13–24 months, 25–36 months and 37–45 months group). ADL, UPDRS motor score and dyskinesia subscore improvement were compared among these groups. No significant difference existed. No life threatening complications occurred. Main side effects included hypophonia, dyskinesia, confusion, depression.

His cognitive function was completely normal. He had no motor palsy and no obvious sensory deficit. His trunk was severely bent forward and continuous dystonic movements occurred mainly in the neck. When he walked, action-induced bending Postoperative course A dramatic reduction in the abnormal muscular tone of the trunk and neck was noted immediately after the initiation of a high frequency stimulation to GPi (Fig. 1). Within several months after surgery, additional progressive improvements were noted.

001). In order to demonstrate the alleviation extent of different motor symptoms, we compared tremor, rigidity, bradykinesia, axial symptoms, facial expression and speech separately. Among all these symptoms, tremor (items 20, 21) was improved best. 65%. Rigidity (item 22), bradykinesia (items 23–26), axial symptoms (items 27–30) and facial expression (item 19) were also improved prominently, although to a lesser extent than tremor. 76%. 99% respectively. In contrast, speech (item 18) subscore comparison between Medoff state before surgery and Medoff=Stimon state after surgery showed no difference.

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